Connexin cell communication channels oviedo orta ernesto kwak brenda r evans william howard. Connexin Cell Communication Channels : Ernesto Oviedo 2019-01-25

Connexin cell communication channels oviedo orta ernesto kwak brenda r evans william howard Rating: 7,2/10 1126 reviews

Connexin cell communication channels : roles in the immune system and immunopathology / editors, Ernesto Oviedo

connexin cell communication channels oviedo orta ernesto kwak brenda r evans william howard

Spanning basic science and potential clinical applications, Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology assembles and synthesizes four decades of the most important research carried out in this field. On receiving a professorship from the Swiss National Science Foundation in 2003, she established an independent research group in the same department to dissect the role of Cxs in atherosclerosis. It additionally describes the latest realizing of the way hole junctions and connexins perform antigen attractiveness, cross-presentation, lymphocyte activation, and within the meeting and serve as of the immunological synapse. Isakson Regulation of Gap Junctions and Cellular Coupling within the Microvasculature in Response to Acute Inflammation; Darcy Lidington and Karel Tyml Impact of Microglial Activation on Astroglial Connexin Expression and Function in Brain Inflammation; Christian Giaume, Nicolas Froger, Juan Andrés Orellana, Mauricio Retamal, and Juan Carlos Sáez A Role for Connexins in Inflammatory Disorders of the Epidermis; Steven Donnelly, Catherine S. Salazar-Onfray Inflammation and Inflammatory Diseases Connexins in Atherosclerosis; Laurent Burnier and Brenda R. The next section examines immunologically related disease scenarios where gap junctions and connexins have been shown to play a fundamental role.

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Connexin Cell Communication Channels : Ernesto Oviedo

connexin cell communication channels oviedo orta ernesto kwak brenda r evans william howard

Finally, the book focuses on the latest progress made on translating the knowledge gained to specific treatment modalities. On receiving a professorship from the Swiss National Science Foundation in 2003, she established an independent research group in the same department to dissect the role of Cxs in atherosclerosis. Finally, the e-book makes a speciality of the most recent development made on translating the data received to precise remedy modalities. This has involved the design and development of small Cx mimetic peptides that block the operation of these channels. This has involved the design and development of small Cx mimetic peptides that block the operation of these channels.

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Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology, 1st Edition (Paperback)

connexin cell communication channels oviedo orta ernesto kwak brenda r evans william howard

Kwak carried out her PhD research work focusing on the regulation of cardiac gap junction channels using a dual patch-clamp approach. During his postgraduate specialist training, he engaged in vaccine research related to diverse infectious agents and diseases, including measles and hepatitis C. A entire view of achievements during this promising box, the publication will tell and replace experts, scientific practitioners, and people learning the potential of advertisement applications. Table of Contents Immunology and Cell Biology Communication in the Immune System by Connexin Channels; Ernesto Oviedo-Orta and William Howard Evans Gap Junctions and Connexins in the Hematopoietic-Immune System: Structural Considerations; Tibor Krenacs, Ivett Zsakovics, Gergo Kiszner, and Martin Rosendaal Approaches for Studying the Role s of Gap Junctions in the Immune System; Aaron M. Topics in this section include approaches for reducing scarring and cardiac arrhythmia, combating inflammation in the central nervous system, and enhancing epithelial tissue repair.

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Connexin Cell Communication Channels: Roles in the Immune by Ernesto Oviedo

connexin cell communication channels oviedo orta ernesto kwak brenda r evans william howard

The contributors explain how gap junctional communication participates in the establishment and maintenance of immunological properties such as antibody and cytokine production, as well as lymphocyte immune surveillance in both physiological and pathological conditions. On receiving a professorship from the Swiss National Science Foundation in 2003, she established an independent research group in the same department to dissect the role of Cxs in atherosclerosis. Plasma membrane-associated channels known as gap junctions, along with their protein building blocks-connexins-have an important functional role in a range of immunological processes, including heart function, cell growth and specialization, and early development. Topics in this section include approaches for reducing scarring and cardiac arrhythmia, combating inflammation in the central nervous system, and enhancing epithelial tissue repair. His interest in intercellular communication via gap junctions spans from 1972 and his group has studied many facets of the structure and function of these Cx-based channels in a variety of normal and pathological situations.

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Connexin Cell Communication Channels

connexin cell communication channels oviedo orta ernesto kwak brenda r evans william howard

Martin Connexin-Based Therapeutical Approaches in Inflammatory Diseases Translating Basic Research on Cx43 Gap Junctions into Therapies for Reducing Scarring and Cardiac Arrhythmia; Robert G. During his postgraduate specialist training, he engaged in vaccine research related to diverse infectious agents and diseases, including measles and hepatitis C. It also describes the most recent understanding of how gap junctions and connexins participate in antigen recognition, cross-presentation, lymphocyte activation, and in the assembly and function of the immunological synapse. Kwak Connexins in Lung Function and Inflammation; Marc Chanson and Michael Koval Effect of Oxidative Stress on Connexins in the Vasculature; Marie Billaud, Scott R. It also describes the most recent understanding of how gap junctions and connexins participate in antigen recognition, cross-presentation, lymphocyte activation, and in the assembly and function of the immunological synapse. The book first provides a historical overview of the discovery of these membrane channels in cells and tissues of the immune system. William Howard Evans, PhD, is professor of medical biochemistry in the Institute of Infection and Immunity at Cardiff University Medical School, United Kingdom.

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Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology

connexin cell communication channels oviedo orta ernesto kwak brenda r evans william howard

Plasma membrane-associated channels known as gap junctions, along with their protein building blocks—connexins—have an important functional role in a range of immunological processes, including heart function, cell growth and specialization, and early development. Cook, Peter Cormie, Colin R. Cook, Peter Cormie, Colin R. She then continued her work for several years as a postdoctoral fellow at the University of Utrecht, the Netherlands. The participants clarify how hole junctional communique participates within the institution and upkeep of immunological homes corresponding to antibody and cytokine creation, in addition to lymphocyte immune surveillance in either physiological and pathological stipulations. It describes their general molecular and biological characteristics and examines how they participate in the evolution, organization, function, and regulation of leukocytes, as well as their interaction with other tissues. She is now associate professor to both the Department of Pathology and Immunology and to the Department of Internal Medicine—Cardiology at the University of Geneva and focuses more broadly on the role of Cxs in cardiovascular physiology and pathology, work that still includes atherosclerotic disease but also restenosis, ischemia? Spanning basic science and potential clinical applications, Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology assembles and synthesizes four decades of the most important research carried out in this field.

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Connexin Cell Communication Channels

connexin cell communication channels oviedo orta ernesto kwak brenda r evans william howard

Chapter 13 -- Translating Basic Research on Cx43 Gap Junctions into Therapies for Reducing Scarring and Cardiac ArrhythmiaChapter 14 -- Connexin-Based Therapeutic Approaches to Inflammation in the Central Nervous System; Chapter 15 -- Enhancing Epithelial Tissue Repair and Reducing Inflammation by Targeting Connexins; Back Cover. Kwak studied at the University of Amsterdam, the Netherlands, where she also obtained her PhD. She is now associate professor to both the Department of Pathology and Immunology and to the Department of Internal Medicine-Cardiology at the University of Geneva and focuses more broadly on the role of Cxs in cardiovascular physiology and pathology, work that still includes atherosclerotic disease but also restenosis, ischemia reperfusion injury of the heart, platelet activation, thrombosis, and the lymphatic system. He also studies their use in addressing cardiac pathology. The book first provides a historical overview of the discovery of these membrane channels in. Abstract: Plasma membrane-associated channels known as gap junctions, along with their protein building blocks-connexins-have an important functional role in a range of immunological processes, including heart function, cell growth and specialization, and early development.

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Connexin Cell Communication Channels: Roles in the Immune by Ernesto Oviedo

connexin cell communication channels oviedo orta ernesto kwak brenda r evans william howard

The book explores the most important technical approaches used and how they have been specially adapted to answer key biological questions particular to the mobile nature of leukocytes. He also studies their use in addressing cardiac pathology. Spanning basic science and potential clinical applications, Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology assembles and synthesizes four decades of the most important research carried out in this field. Green Enhancing Epithelial Tissue Repair and Reducing Inflammation by Targeting Connexins; David L. The book explores the most important technical approaches used and how they have been specially adapted to answer key biological questions particular to the mobile nature of leukocytes.

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Connexin Cell Communication Channels : Ernesto Oviedo

connexin cell communication channels oviedo orta ernesto kwak brenda r evans william howard

Shoji, and Juan Carlos Saez Connect the Immune System: Roles of Gap Junctions in Antigen Presentation and T Cell Activation; Baoxu Pang and Jacques Neefjes Gap Junctions and Connexins in the Immune Defense against Tumors; Flavio A. The e-book first offers a historic review of the invention of those membrane channels in cells and tissues of the immune method. Salazar-Onfray Inflammation and Inflammatory Diseases Connexins in Atherosclerosis; Laurent Burnier and Brenda R. Kwak studied at the University of Amsterdam, the Netherlands, where she also obtained her PhD. Green Enhancing Epithelial Tissue Repair and Reducing Inflammation by Targeting Connexins; David L. It also describes the most recent understanding of how gap junctions and connexins participate in antigen recognition, cross-presentation, lymphocyte activation, and in the assembly and function of the immunological synapse.

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